Evolution of Metabolic Pathways
نویسندگان
چکیده
منابع مشابه
Evolution of dominance in metabolic pathways.
Dominance is a form of phenotypic robustness to mutations. Understanding how such robustness can evolve provides a window into how the relation between genotype and phenotype can evolve. As such, the issue of dominance evolution is a question about the evolution of inheritance systems. Attempts at explaining the evolution of dominance have run into two problems. One is that selection for domina...
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The adaptive significance of enzyme variation has been of central interest in population genetics. Yet, how natural selection operates on enzymes in the larger context of biochemical pathways has not been broadly explored. A basic expectation is that natural selection on metabolic phenotypes will target enzymes that control metabolic flux, but how adaptive variation is distributed among enzymes...
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Information is missing from the Acknowledgments section. The Acknowledgments should include the following text: We thank Igor Grigoriev, Adrian Tsang, Andriy Sibirny, Antonio Logrieco, Burt Bluhm, Christian Kubicek, Dan Cullen, David Archer, Donald Nuss, Gillian Turgeon, Jason Stajich, Jennifer Wortman, Joey Spatafora, Johannes Hackstein, John Davis, Luis Corrochano, Mary Berbee, Nada Krasevec,...
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Fungi contain a remarkable range of metabolic pathways, sometimes encoded by gene clusters, enabling them to digest most organic matter and synthesize an array of potent small molecules. Although metabolism is fundamental to the fungal lifestyle, we still know little about how major evolutionary processes, such as gene duplication (GD) and horizontal gene transfer (HGT), have interacted with cl...
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The rapid expansion of the field of biotechnology during the past decade has resulted in an increase in the use of enzymes in biocatalytic processes. However, limited stability as well as limited catalytic activity of many biocatalysts under process conditions, which differ greatly from conditions found in biological environments, demands design of improved enzyme catalysts. Rational design str...
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ژورنال
عنوان ژورنال: Zoological Research
سال: 2008
ISSN: 0254-5853
DOI: 10.3724/sp.j.1141.2008.00459